Inspired by Chen et al 2024.[1] AI generated image of an astrocyte in the hippocampus. EA – electroacupunctureCIPN – chemotherapy-induced peripheral neuropathyIF – impact factorAAV – adeno-associated virusRVM – rostral ventromedial medullaDREADDs – designer receptors exclusively activated by designer drugsIP3 – inositol triphosphatehPMCA2 – human plasma membrane Ca2+ channelZP – Zongping (an extra point 1cun … Continue reading EA astrocytes and CIPN 2024
Category: Experimental
KOR and depression after CSDS
Stimulated by Wang et al 2023.[1] Supplemental Figure 2 from Wang et al 2023 showing development of animal models of SDS. KOR – κ opioid receptorCSDS – chronic social defeat stressSSDS – subthreshold social defeat stressSDS – social defeat stressAAV – adeno-associated virus key to acronyms This is a potentially important paper that describes, for … Continue reading KOR and depression after CSDS
HRV predicts placebo response in men
Stimulated by Krecké et al 2023.[1] Mike receiving a thermal pain stimulus to his ventral forearm under the watchful eye of colleagues in Greifswald (2023). HRV – heart rate variabilityCCK – cholecystokinin key to acronyms I have always been intrigued by placebo and nocebo effects as well as the more subtle differences between men and … Continue reading HRV predicts placebo response in men
STP and the DH 2023
Stimulated by Cathenaut et al 2023.[1] Graphic drawn by MC in the late 90's at the request of AW for a paper in the BMJ.[2] STP – short term plasticityDH – dorsal horn (the sensory horn of the spinal cord)EA – electroacupunctureCirca – approximately (sometimes shortened to c)TRPV1 – transient receptor potential vanilloid type 1GABA … Continue reading STP and the DH 2023
EA for intestinal barrier function in IBS and UC 2023
Stimulated by Liu et al 2023.[1] Volcano plots from Figure 1 of Liu et al 2023.[1] EA – electroacupunctureIBS – irritable bowel syndromeUC – ulcerative colitisDSS – dextran sodium sulphateDEGs – differentially expressed genesGSEA – gene set enrichment analysis key to acronyms This paper came up in one of my searches in the last week … Continue reading EA for intestinal barrier function in IBS and UC 2023
Acupuncture for acute arthritis 2023
Stimulated by Yu and Kim 2023.[1] Figure summarising mechanisms from Yu and Kim 2023.[1] MA – manual acupunctureEA – electroacupunctureSR – systematic reviewPWL – paw withdrawal latencyPWT – paw withdrawal thresholdRoB – risk of biasWMA – Western medical acupunctureNSAIDs – non-steroidal anti-inflammatory drugs key to acronyms I have long pondered on the difference between what … Continue reading Acupuncture for acute arthritis 2023
FM and anti-SGC IgG 2023
Stimulated by Krock et al 2023.[1] Angel of the West is an outdoor sculpture in Jupiter, Florida, United States. The sculpture was made in 2008 by German sculptor Julian Voss-Andreae and was created based on an antibody structure published by E. Padlan for the Florida campus of the Scripps Research Institute. The antibody is placed into a ring referencing Leonardo da Vinci's Vitruvian Man highlighting … Continue reading FM and anti-SGC IgG 2023
Pre-EA on spinal WDRs
Stimulated by Yu et al 2023.[1] Image from part of Figure 1 in Yu et al 2023.[1] EA – electroacupunctureWDR – wide dynamic range (neurones that respond to non-noxious and noxious inputs)SDH – spinal dorsal hornHS – hypertonic salineRF – receptive field key to acronyms This paper comes from Professor Jing’s team in Beijing and … Continue reading Pre-EA on spinal WDRs
EA for PSD
Stimulated by Yao et al 2023.[1] PSD – post-stroke dysphagiaIF – impact factorEA – electroacupunctureaka – also known asROS – reactive oxygen speciesM1 – primary motor cortexPBN – parabrachial nucleusNTS – nucleus tractus solitarius key to acronyms I am pretty selective about choosing laboratory studies to highlight on the blog. I do not have direct … Continue reading EA for PSD
Muscle vs fascia in LBP
Inspired by Cozacov et al 2022 and others.[1–3] Photo by Juan Pablo Serrano Arenas on Pexels.com LBP – low back painQL – quadratus lumborumHC – healthy controlUS – ultrasoundNRS – numerical rating scaleLTR – local twitch responseFM – fibromyalgiaOA – osteoarthritisDOMS – delayed onset muscle soreness key to acronyms This is a small but interesting … Continue reading Muscle vs fascia in LBP










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