ST36 EA for visceral hypersensitivity and indirect VNS

Stimulated by Chen et al 2020,[1] and Courties et al 2021.[2] Photo by Sora Shimazaki on Pexels.com EA – electroacupunctureIF – impact factorIBD – inflammatory bowel diseaseNGF – nerve growth factorTrkA – tropomyosin receptor kinase A (high affinity NGF receptor)TRPV1 – transient receptor potential vanilloid 1 (aka capsaicin receptor)DRGs – dorsal root gangliaCAP – cholinergic … Continue reading ST36 EA for visceral hypersensitivity and indirect VNS

EA vs Prucalopride in SCC

Stimulated by Liu et al 2020.[1] Protocol in Liu et al.[1]Diagram by MC. EA – electroacupunctureSCC – severe chronic constipationIF – impact factorCSBM – complete spontaneous bowel movement5–HT4 – 5–hydroxytryptamine 4 receptorkey to acronyms This paper came out in December 2020, and I have been sitting on it ever since waiting for the urge to … Continue reading EA vs Prucalopride in SCC

Functional dyspepsia 2020

Image by Paweł Czerwiński on Unsplash. The main paper this week was an obvious choice as it is a big clinical trial published in a mainstream general medicine journal. Currently the paper has not surfaced on PubMed, although it is published online. I was tipped off by an email from the journal editor as I had been one … Continue reading Functional dyspepsia 2020

Gastroparesis 2018

On the 18th December another Cochrane Review popped up on my daily PubMed search: Acupuncture for symptomatic gastroparesis.[1] Cochrane reviews are substantial pieces of work, with numerous peer and editorial review stages built in to the process. The rigorous approach to assessing bias and the adoption of the GRADE system to summarise findings often results … Continue reading Gastroparesis 2018

EA for chronic severe functional constipation

– it seems to work after an intensive course... This blog was first published on 28th November 2017 on https://blogs.bmj.com/aim/ Photo by Pixabay on Pexels.com About a year ago I was surprised to see a sham controlled RCT of electroacupuncture (EA) published in Annals of Internal Medicine.[1] I was surprised for several reasons: I review for … Continue reading EA for chronic severe functional constipation