Inspired by Titiz et al 2024.[1] AI generated image. SCs – Schwann cellsIF – impact factorAMA – abdominal mechanical allodyniaPMA – periorbital mechanical allodyniaHMA – hind paw mechanical allodyniaC5a – a small soluble pro-inflammatory peptide that functions as an anaphylatoxinDAMPs – damage-associated molecular patternsC5aR1 – C5a receptor 1GPCR – G protein-coupled receptorNLRP1 – NOD-like receptor … Continue reading SCs in endometriosis pain 2024
Stimulated by Clauw et al 2023 and Cho et al 2023.[1,2] Photo by Cameron Venti on Unsplash. FM – fibromyalgiaIF – impact factorSGC – satellite glial cellDRG – dorsal root ganglionMSK – musculoskeletalHR – hazard ratioaHR – adjusted hazard ratio key to acronyms I was curious to see this debate on FM published in Autoimmune … Continue reading Is FM an autoimmune disease?
Stimulated by Di Carlo et al 2023 and Treister-Goltzman et al 2023.[1,2] Photo by Mattia Golinucci on Unsplash. An ancient church in a cave, il tempio del valadier, the valadier's temple in Ancona. Di Carlo et al are from the same region of Italy. FM – fibromyalgiaMA – manual acupunctureBMI – body mass indexFIQR – … Continue reading Acupuncture for FM 2023
Stimulated by Krock et al 2023.[1] Angel of the West is an outdoor sculpture in Jupiter, Florida, United States. The sculpture was made in 2008 by German sculptor Julian Voss-Andreae and was created based on an antibody structure published by E. Padlan for the Florida campus of the Scripps Research Institute. The antibody is placed into a ring referencing Leonardo da Vinci's Vitruvian Man highlighting … Continue reading FM and anti-SGC IgG 2023
Inspired by Ferreira et al 2023.[1] Photo by Suzy Hazelwood on Pexels.comI chose an image that looks a bit like one formulation of duloxetine – the SNRI that probably figures most prominently in the research discussed. NICE – National Institute for Health and Care ExcellenceSR – systematic reviewSNRIs – serotonin-norepinephrine reuptake inhibitorsCI – confidence intervalMCID … Continue reading Antidepressants for pain 2023
Inspired by Goebel et al 2021.[1] Graphical abstract from Goebel et al 2021. FMS – fibromyalgia syndromeFM – fibromyalgiaIgG – immunoglobulin GIF – impact factorHC – healthy controlsCM – C-mechanoreceptorCMC – cold-sensitive CMDRGs – dorsal root gangliaSGCs – satellite glial cellsMTrPs – myofascial trigger pointsSHA – self home acupunctureST36 – an area in upper tibialis … Continue reading Transfer of FMS with IgG
Stimulated by NG193.[1] Photo by Arno Smit on Unsplash. NICE – National Institute for Health & Care ExcellencecLBP – chronic low back painMSK – musculoskeletalGERAC – German acupuncture trials (large 3 arm trials with ~1000 patients in each)MCID – minimum clinical important differenceLA – local anaestheticCRPS – complex regional pain syndromeRFD – radiofrequency denervation. key … Continue reading Consider acupuncture for chronic pain
Inspired by Katz et al 2020,[1] and Ma et al 2020.[2] Photo by Pixabay on Pexels.com - I guess the image was just shouting hazard ratio at me 😉 FM – fibromyalgiaVAS – visual analogue scalePPT – pressure pain thresholdHR – hazard ratio key to acronyms I have a couple of really interesting papers on … Continue reading FM and stroke risk
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